About ConcePTION

ConcePTION is a project funded by the Innovative Medicines Initiative, a private public partnership. The project was launched in April 2019.

We believe that we have an important societal obligation to radically and rapidly reduce uncertainty about the effects of medication used during pregnancy and breastfeeding to benefit women in making informed decisions about medications used before, during and after pregnancy.

Reporting medicine use in pregnancy

Did you use any medicines when you were pregnant? Here is how you and your health care provider can report what we call an exposure.

Ten principles for stakeholder engagement in the ConcePTION project

The ConcePTION project is building much-needed knowledge for women and health care professionals. To achieve our goal of building an ecosystem for medicine safety in pregnancy and breastfeeding, we need to engage with women, their partners, their doctors, pharmacists, midwives and nurses, the companies that develop medicines and the authorities that approve them and decide what becomes available to patients. Our goal is to work in an open and inclusive way, with the spirit of mutual respect and trust. Here is how we engage with stakeholders in an ethical way.


Women often use medicines while breastfeeding, but we have very little information on how the mother’s medicines affect the breastfed infant. Researchers in the ConcePTION project have developed a generic work flow for predicting medicine concentrations in breast milk using physiologically-based pharmacokinetic (PBPK) modelling, just published in Pharmaceutics.  | READ MORE >>
On 20 April 2023, we organised a webinar on using real word data for research on medication safety during pregnancy and breastfeeding. During the webinar, Miriam Sturkenboom & Marieke Hollestele from University Medical Center Utrecht, the Netherlands, Rosa Gini from Agenzia regionale di sanita della Toscana, Italy and Vjola Hoxhaj from University Medical Center Utrecht, the Netherlands discussed the opportunities and challenges of using real-world data to investigate the safety of medications during pregnancy and breastfeeding. | READ MORE >>
Where can we find data that links infant outcomes, breastfeeding and medicine exposure? A new systematic scoping review from ConcePTION shows that the information that is available is not enough. And calls for action to provide long term population-based data and to monitor infants for adverse effects. | READ MORE >>


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The ConcePTION consortium

The project unites an unprecedented 88 organizations from 22 countries, including the European Medicines Agency, drug manufacturers, academia, public health organizations, and teratology networks to innovate new solutions to a decades-long public health issue.


The ConcePTION project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 821520. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.